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・ Biothermia
・ Biotic
・ Biotic Baking Brigade
・ Biotic component
・ Biotic ethics
・ Biotic index
・ Biotic Ligand Model
・ Biotic material
・ Biotic potential
・ Biotic stress
・ Biotie Therapies
・ BioTime
・ Biotin
・ Biotin attachment domain
・ Biotin carboxyl carrier protein
Biotin carboxylase
・ Biotin deficiency
・ Biotin hydrazide
・ Biotin PEG2 amine
・ Biotin sulfoxide
・ Biotin synthase
・ Biotin-dependent malonate decarboxylase
・ Biotin-independent malonate decarboxylase
・ Biotinidase
・ Biotinidase deficiency
・ Biotinylated dextran amine
・ Biotinylated retinoids
・ Biotinylation
・ Biotin—(acetyl-CoA-carboxylase) ligase
・ Biotin—(methylcrotonoyl-CoA-carboxylase) ligase


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Biotin carboxylase : ウィキペディア英語版
Biotin carboxylase

In enzymology, a biotin carboxylase () is an enzyme that catalyzes the chemical reaction
:ATP + biotin-carboxyl-carrier protein + CO2 \rightleftharpoons ADP + phosphate + carboxybiotin-carboxyl-carrier protein
The 3 substrates of this enzyme are ATP, biotin-carboxyl-carrier protein, and CO2, whereas its 3 products are ADP, phosphate, and carboxybiotin-carboxyl-carrier protein.
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming). This enzyme is also called biotin carboxylase (component of acetyl CoA carboxylase). This enzyme participates in fatty acid biosynthesis.
A C-terminal conserved domain within this enzyme contains most of the active site residues.
==Structural studies==

, 5 structures have been solved for this class of enzymes, with PDB accession codes , , , , and .

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